Will Forte

Shaggy Rogers (voice)

Mark Wahlberg

Blue Falcon (voice)

Jason Isaacs

Dick Dastardly (voice)

Gina Rodriguez

Velma Dinkley (voice)

Zac Efron

Fred Jones (voice)

Amanda Seyfried

Daphne Blake (voice)

Kiersey Clemons

Dee Dee Skyes (voice)

Ken Jeong

Dynomutt (voice)

Tracy Morgan

Captain Caveman (voice)

Frank Welker

Scooby-Doo / Pterodactyl (voice)

Iain Armitage

Young Shaggy (voice)

Mckenna Grace

Young Daphne (voice)

Pierce Gagnon

Young Fred (voice)

Ariana Greenblatt

Young Velma (voice)